By Robert H. Rosa Jr., MD
This quantity is split into elements: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: medical facets. half I makes use of a hierarchy that strikes from common to express to assist derive a differential analysis for a selected tissue. half II is a compilation of chosen scientific elements of value to the final ophthalmologist. Following half II are the yankee Joint Committee on melanoma 2010 staging varieties for ocular and adnexal tumors. This revised textual content includes quite a few new pathologic and scientific photos. significant revision 2011-2012.
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Additional resources for 2011-2012 Basic and Clinical Science Course, Section 4: Ophthalmic Pathology and Intraocular Tumors (Basic & Clinical Science Course)
Originally, the retinal opacification seen clinically was thought to result from retinal edema (extracellular accumu lation of fluid), but experimental evidence shows that a disruption in the architecture of the photoreceptor elements causes the loss of retinal transparency. Retinal dialysis is most likely to develop in the inferotemporal or superonasal quad~ rant. The retina is anchored anteriorly to the nonpigmented epithelium of the pars plana. This union is reinforced by the attachment of the vitreous base, which straddles the ora serrata.
Courtesy of Hans E. ) CHAPTER 3: Specimen Han dli ng . 31 Table 3-2 Common Stains Used in Ophthalmic Pathology Stain Material Stained: Color Example Hematoxylin and eos in (H& E) Nucleus: blu e Cytoplasm: red Glycogen and proteog lycans: magenta Acid mucopolysaccharide: bl ue Calcium: red Acid muco polysaccharide: blue Amylo id: orange, red-green dichroism Ac id-fast orga ni sms: red Fungal elements: black Gene ral tissue stain (Fig 3-2EI Descemet membrane (Fig 6-17EI Cave rn ous optic atrophy (Fig 15-1 0BI Band ke ratopathy Macular dystrophy (Fig 6-21CI Lattice dy strophy (Fig 6-23C, DI Atypica l m ycobacterium Fusarium (Fig 6-7B) Amyloid: pu rp le, violet Bacteria positive: blue Bacteria neg ative: red Lattice d ystrop hy Bacteria l infection Collagen: blue Granul ar dystrophy (F ig 6-22CI Red depos its Hemosi d erosis bulbi Lattice dystrophy Temporal artery elastic laye r Band ke rat opathy (Fig 6-1 2CI Periodic acid-Schiff (PAS) Alcian blue Alizarin red Colloidal iron Congo red Ziehl-Neelsen Gomori methenamine silver (GMSI Crystal violet Gram stain (tissue Brown & Brenn IB&BI or Brown & Hopps IB&Hl stain ) Masson trichrome Perls Prussian blue Thioflavin T (ThT) Verhoeff-van Gieson von Kassa Musc le: red Iron : blue Amyloid: flu orescent yellow Elastic fibers: black Calcium p hosp hate salts: bl ack CHAPTER 4 Special Procedures New technologies have contributed to improvements in the diagnosis of infectious agents and tumors as well as to the classification of tumors, especially the non-Hodgkin lymphomas (NHLs), childhood tumors, and sarcomas.
T he anterio r chamber angle structu res, especiall y the trabecu lar beams, are vul nerable to distortion of the anterior globe. Cyclodialysis results from dis insertion of the lon gitudina l muscle of the ci liary bo dy fro m the scleral spur (Fig 2-5). T his condit ion ca n lead to hypoton y because the ,aqueous of the anterior chamber now has free access to the sup rac horoidal space; and beca use the blood supply to the cil ia ry body is d imi n ished , the p roduction of aqueous is decreased.
2011-2012 Basic and Clinical Science Course, Section 4: Ophthalmic Pathology and Intraocular Tumors (Basic & Clinical Science Course) by Robert H. Rosa Jr., MD